Development of sustained release Aceclofenac lipid matrix tablet using continuous melt granulation technique
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Diclofenac Sodium Sustained Release Tablets Using Melt Granulation Technique
Hydrophilic polymers alone are not quite efficient in controlling the release of highly water soluble drugs. Hydrophobic Polymer and pore forming agent have been extensively investigated for sustaining the release of drug. They provide several advantages include good stability at varying pH ranges and effectively retards the water soluble drug. In the present study it was a novel approach where...
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The study was obtained to develop oral controlled release matrix tablets of Lamivudine having different proportion of Guar gum (retardant polymer) and to study the effect of formulation factor such as polymer proportion on the invitro release. The prepared granules were evaluated such as angle of repose, loose bulk density, tapped bulk density and compressibility index and satisfactory results ...
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Till date, most of the drugs have been given in conventional immediate release dosage form. Nimorazole is an anticancer drug, used as a hypoxic radiosensitizer in patients undergoing radiotherapy and no formulation has been available in the market till now. Hence, for the purpose to develop an immediate release dosage form, a statistical optimization process has been employed to quantify the ef...
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ژورنال
عنوان ژورنال: American Journal of PharmTech Research
سال: 2018
ISSN: 2249-3387
DOI: 10.46624/ajptr.2018.v8.i3.020